Veterinary Anesthesia & Analgesia Support Group
Practical Information for the Compassionate Veterinary Practitioner
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    O Drugs
    Alphabetical Drug Summaries
    Dr. Bob Stein


a)      Classification

i)        A pure Mu opioid agonist

b)      General Information

i)        Duration of effect is 4 to 6 hours

c)      Advantages/Recommended use

i)        General premed for anesthetic candidates in all categories

ii)       Hypotensive patients

(1)   Unlike morphine, should not cause transient hypotension

iii)     Higher risk patient when the risk of vomiting needs to be minimized

d)      Cautionary Information

i)        Bradycardia is common

ii)       Noise hypersensitivity may be a problem

iii)     There is moderate sedative synergism between oxymorphone and acepromazine in the dog

(1)   Acepromazine doses must kept at the lower end of the dose range

iv)     Should be used with caution in the cat if no sedative/tranquilizer is used

e)      Dosage Information

i)        Dog – 0.05 to 0.1 mg/kg (0.025 - 0.050 mg/lb) IM, IV

ii)       Cats – 0.025 to 0.05 mg/kg (0.01 - 0.025 mg/lb) IM, IV

(1)   Combine with acepromazine 0.01 to 0.05 mg/kg (0.005 to 0.025 mg/lb) or medetomidine 0.001 to 0.015 mg/kg (0.0005 to 0.0075 mg/lb)

f)       Cost

i)        High

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Last modified: February 16, 2011 .